Depression – Biological causes

Chemicals / Neurotransmitters:
Neurotransmitters are the chemical messengers, which are critical in the transmission of nerve impulses in our brain and nerves. The level of certain neurotransmitters, NORADRENALINE & SEROTONIN are decreased in the brain. Most of the medications used for treating depression (Anti depressants) help in elevating the levels of these chemicals in the brain.

Genetic: For every possible physical and mental feature there is a gene in our cells. So is a gene for Depression. The parents of a depressed person are at a higher risk for depression. If a sibling has depressive illness then there is a 15% chance, that it will be there in another sibling .If the onset of depression is after the age of 40 yr. then chance of it being genetically transmitted is less.

Hormonal imbalance: Though the exact mechanisms are not understood but imbalance of female sex hormones can lead to depression. Depressions in the postmenopausal and post partum (after delivery) period are the examples.

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