Different Kinds of Thalassemia

Generally, Thalassaemia can be classified into two categories based on the globin molecule which is affected and these two categories are the alpha (a) thalassaemia and the beta (ß) thalassaemia.

The most severe form of alpha thalassemia results in fetal or newborn death. Most individuals with alpha thalassemia have milder forms of the disease, with varying degrees of anemia.

Beta thalassemias range from very severe to having no effect on health.

   – Thalassemia major, the most severe form, is also called Cooley’s anemia, named after the doctor who first described it in 1925.
   – Thalassemia intermedia is a mild Cooley’s anemia.
   – Thalassemia minor (also called thalassemia trait) may cause no symptoms, but changes in the blood do occur.


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