Causes of Dementia

Causes The cause of Dementia is still unknown. There probably is not one single cause, but several factors that affect each person differently. The number of people with the disease doubles every 5 years beyond age 65.Family history is another risk factor. The more common form of Demantia is known as late-onset. It occurs later in life, and no obvious inheritance pattern is seen in most families. However, several risk factor genes may interact with each other and with non-genetic factors to cause the disease. The only risk factor gene identified so far for late-onset Alzheimer’s disease is a gene that makes one form of a protein called apolipoprotein E (ApoE). Everyone has ApoE, which helps carry cholesterol in the blood. Only about 15 percent of people have the form that increases the risk of AD. It is likely that other genes also may increase the risk of AD or protect against AD, but they remain to be discovered.



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