Symptoms of Anosmia

The disease usually begins in late childhood with increasing night blindness due to degeneration of the retina (retinitis pigmentosa) and loss of the sense of smell (anosmia). If the disease progresses, other symptoms may include deafness, problems with balance and coordination (ataxia), weakness or numbness (peripheral neuropathy), dry and scaly skin (ichthyosis), and heartbeat abnormalities (cardiac arrhythmias). With the loss of sense of smell there can also be a loss of taste. Distortion of function-foods or odors that normally are pleasant may taste or smell odd or distorted, perhaps with an unpleasant smell. Some individuals will have shortened bones in their fingers or toes, or a visibly shortened fourth toe.  Although the disease usually appears in early childhood, some people will not develop symptoms until their 40s or 50s.



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